Effect of goserelin in quality of life of women with abnormal uterine bleeding and leiomyoma: a case series

Leiomyomas are a major source of morbidity and decrease in quality life for women reproductive age. Goserelin is Gonadotrophin-releasing hormone agonist (GnRHa) which treats leiomyomas inducing hypogonadotropic state. Adverse effects includes hot flushes vaginal dryness. When choosing treatment, its capability to improve the patient’s must be taken consideration. The objective this retrospective case series was study impact with abnormal uterine bleeding refractory hormonal contraceptives. In study, twenty-three due leiomyoma who were treated at two tertiary public teaching hospitals from Brazil answered UFS-QoL regarding their symptoms before after using other questions experience Goserelin. It observed that Symptom severity scale Health-related all 6 domains had an improvement live use has 37 there questions. Most participants experienced (78.2%). Amenorrhea achieved 82.9% participants. Fifteen (68.1%) Therefore effective leiomyomas, although, dryness common adverse effects.